Home » Journal nummers » Jaargang 9, Abstractboek, Maart 2012

Inhoudsopgave Jaargang 9, Abstractboek, Maart 2012

DAG 1 - WOENSDAG 25 JANUARI

A Good Manufacturing Practice procedure to generate therapeutic numbers of highly pure anti-leukemic virus-specific T-cells
The Aryl hydrocarbon Receptor antagonist StemRegenin1 promotes expansion of immature hematopoietic progenitors
Generation of allo-HLA restricted T-cells with potent B-cell reactivity using MHC tetramer pull down carries the risk of off-target reactivity
Pre-clinical evaluation of -generated natural killer cells as immunotherapeutic product against acute myeloid leukemia
The Origin and Nature of Tightly Clustered BTG1 Deletions in Precursor B-cell Acute Lymphoblastic Leukemia Support a Model of Multiclonal Evolution
Developing thymic regenerative therapy by generating thymic epithelial precursor cells from induced pluripotent stem cells
Towards immunotherapy of acute myeloid leukemia with allogeneic NK cells generated from umbilical cord blood hematopoietic progenitor cells
miR34-a and FOXP1 are involved in a negative feedback loop responding to double-stranded DNA breaks in developing B cells
Endocrine late sequelae in long-term survivors of childhood non-Hodgkin lymphoma
Persistent fatigue among (long-term) non-Hodgkin lymphoma survivors: results from the longitudinal population-based PROFILES registry in the South of the Netherlands
Optimal treatment sequencing in patients with multiple myeloma not eligible for stem cell transplantation: modelling as a solution to questions that trials can’t answer?
Quantitative in-vivo monitoring of bone formation in multiple myeloma patients following treatment with bortezomib: a pilot study
Induction of TAp73 expression by platinum-based compounds to overcome drug resistance in p53 dysfunctional chronic lymphocytic leukemia
Synergistic Action of the Human Inhibitory KIR Antibody IPH2102, and the Human CD38 Antibody Daratumumab to Enhance the Lysis of Primary Multiple Myeloma (MM) Cells in the Bone Marrow Mononuclear Cells (MNCs) from Myeloma Patients
Bortezomib restores defective apoptosis by up-regulation of Noxa in Enteropathy-associated T-cell Lymphoma
Identification of miR-155 targets in Burkitt lymphoma
Acetylation of C/EBPε is functionally important during neutrophil development
Interferon-gamma Impairs The Self-Renewal Of Hematopoietic Stem Cells
The E3 ubiquitin ligase Triad1 prevents chromosomal missegregation by regulating the checkpoint kinase Bub1
CITED2 Modulates Differentiation and Proliferation of Normal and Leukemic Hematopoietic Stem and Progenitor Cells Downstream of PU.1
Occurence of T cells specific for the proteins Crf1 and Catalase1 in SCT patients recovering from invasive aspergillosis
The chemokine receptor CXCR3 is required for the efficient recruitment of bone marrow-resident memory T cells to inflamed tissues
Multipotent Vδ2-negative γδT-cells after CMVreactivation in allogeneic stem cell transplantation
Decreased levels of circulating CCR6CD161CD8 T cells harboring cyclosporine resistance are associated with the development of graft-versus-host disease
Keynote: Antigen presentation Understanding and manipulating antigen presentation by MHC class II molecules
Molecular dissection of signals provided by activated T cells to CLL cells indicates major role for IL-21 and CD40 in controlling proliferation and chemoresistance
A High-Risk Survival Signature for Multiple Myeloma
The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia
Multiple HLA class I and II associations in classic Hodgkin lymphoma and EBV status defined subgroups
Towards Personalized Medicine Using a Novel Preclinical Model: Identifying Daratumumab as Effective Treatment for Multiple Myeloma
APRIL is present in the microenvionment of CLL, and affects disease progression in the TCL-1 transgenic mouse model
Improving human monocyte-derived dendritic cell vaccines by lipid nanoparticle-mediated delivery of PD-L1 and PD-L2 siRNA
Collateral Damage of Non-hematopoietic Tissue by Hematopoiesis-specific T Cells Results in GvHD During an Ongoing Profound GvL Reaction
Apoptotic blebs from leukemic cells as a source of tumor associated antigen for monocyte-derived dendritic cell loading
B and T lymphocyte attenuator mediates inhibition of MiHA-specific CD8 T cells in allogeneic stem cell transplantation patients
Rapid identification and expression analysis of minor histocompatibility antigens by whole genome association scanning and microarray gene expression analysis
Identification of New Hematopoietic Minor Histocompatibility Antigen UTA2-1; Applicable in Antitumor Immunotherapy
Constitutional t(16;21)(p13;q22) as a novel pathogenomic mechanism in a series of three new mutated FPD/AML pedigrees: implications for diagnostics
Combination of CD34/CD38 Immunophenotypes and Side Population (SP) reveals the Putative Leukemia Stem Cell/Leukemia Initiating Cell in Acute Myeloid Leukemia
High miR-212 expression predicts for better survival in cytogenetically and molecularly heterogeneous AML
Prognostic pre-transplant factors in myelodysplastic syndromes primarily treated by allogeneic HSCT: an EBMT study
High GATA-2 expression is a poor prognostic marker in pediatric Acute Myeloid Leukemia
New multiparameter approach for the identification of leukemic stem cells in acute myeloid leukemia patients
Expression of c-Met in tumor cells correlates with favorable outcome in classical Hodgkin lymphoma
Identification of a Novel B-CLL Subset Expressing Mutated Stereotypic B-Cell Receptors with Specificity for Yeast Mannan
Microenvironment Shields Myeloma from Adoptive Immunotherapy by Cell Adhesion Mediated Immune Resistance (CAM-IR)
hsTRAIL/Apo2L-Induced Apoptosis in Enteropathy-Associated T-Cell Lymphoma
Is there a germinal centre-like and activated B-cell like diffuse large B-cell lymphoma miRNA profile?
The molecular targets of Dasatinib involved in conferring CD40-mediated drug resistance in chronic lymphocytic leukemia
Deep-sequencing investigation into and KRAS mutations in myeloid malignancies
Preliminary Results from a Phase III Trial of Imatinib Versus Imatinib in Combination with Cytarabine in Patients with First Chronic Phase Myeloid Leukemia
Treatment with Lenalidomide in myelodysplastic syndromes with 5q deletion: results from the Dutch named patient program (NPP)
High Dose (HD-AraC) vs Standard Dose Cytosine Arabinoside (SD-AraC) during Induction and IL-2 vs Observation after Consolidation/Autologous stem cell transplantation in patients with Acute Myelogenous Leukemia (AML): Final report of the AML-12 randomized phase III trial of EORTC and GIMEMA Leukemia Groups on the value of High Dose AraC
The Impact of Prophylactic Fresh Frozen Plasma On Venous Thromboembolism in Adults Treated for Acute Lymphoblastic Leukemia
The direct treatment costs for patients with acute myeloid leukemia
Erythropoiesis and globin switching in compound mutant mice
Regulation of erythrocyte shape through LYN-induced tyrosine phosphorylation and downstream events
Identification of novel cytokines and chemokines that induce HSC expansion
The transcription factor MEIS1 regulates early erythroid and megakaryocytic cell fate
Central memory CD8 T cells regulate hematopoietic stem cell function
Mouse versus human extrinsic cues dictate transformation potential in BCR-ABL/BMI1-induced leukemia in human xenograft models

DAG 2 - DONDERDAG 26 JANUARI

CEBPα Is a Transcriptional Repressor of T-Cell Related Genes Explaining the Myeloid/T-Lymphoid Features of CEBPα-Silenced AML
GFI1 is a direct target of the oncofusion protein AML1-ETO in acute myeloid leukemia
Polycomb Group Complex 1 Composition determines Hematopoietic Stem Cell fate
Mutations in TET2 and IDH in patients with acute myeloid leukemia perturb a common epigenetic pathway resulting in decreased 5-hydroxymethylcytosine levels
Genetic defects in PRC2 components other than are not common in myeloid malignancies
PRC1 complex composition dictates locus-specific polycomb-mediated repression in human stem/progenitor cells
Flow cytometry in myelodysplastic syndromes. Definitions, Clinical and Diagnostic Applications
Rol van multiparameter flowcytometrie bij multipel myeloom
Trombo-elastografie en massaal bloedverlies
Double hit lymfoom
Multiple Myeloma Recent developments and controversies
Maligne lymfoom, nieuwe ontwikkelingen op gebied van imaging
The extracellular matrix protein Slit3 promotes erythropoiesis
Matrix protein βig-h3 function in hematopoietic and stromal cells
Plasma Membrane proteomics on human HSCs/MPPs/LSCs
The role of the class III PI3K Vps34 in regulation of normal and malignant hematopoiesis
In vivo T-cell depletion using rabbit derived ATG leads to an increased EBV-PTLD risk due to an induced imbalance between B and T-cell recovery which is not seen after horse derived ATG or alemtuzumab
Promising efficacy of combined inolimomab and etanercept in severe steroid-refractory acute graft-versus-host disease (aGVHD)
Treatment of steroid resistant grade II to IV acute GVHD by infusion of mesenchymal stroma cells expanded with human plasma and platelet lysate – a phase I/II study
Improved outcome following Intensive Care Unit support within 100 days after allogeneic Haematopoietic Stem Cell Transplant
R-DHAP Immuno-Chemotherapy Is An Effective Remission-Induction Treatment for Fludarabine Refractory CLL Patients: Interim Analysis of the Dutch-Belgian Prospective Multicenter HOVON88 Trial
Diminished Asparaginase Turnover Due to a Germline Mutation in Cathepsin B
Alemtuzumab treatment can affect CD52 positive as well as CD52 negative GPI-deficient Sizary cells allowing long-term disease control
Are we on the right track? Incidence, survival and mortality from plasma cell malignancies in the Netherlands in the last two decades: results from a population based study
Gene expression profiling, high-density genome-wide genotyping and copy number analyses of adult acute lymphoblastic leukemia
High class II-associated invariant chain peptide (CLIP) expression on residual leukemic cells is associated with increased relapse risk in acute myeloid leukemia
MicroRNA Expression Profiling of Hematopoietic and Leukemic Stem Cells in Acute Myeloid Leukemia
Exome Sequencing of Late Recurrence T-Cell ALL in Children Confirms Second Leukemia and Exposes Predisposition Candidate Genes
Targeting of Acute Myeloid Leukemia (stem) cells by anti-CLEC12A Antibody-Drug-Conjugates and Bispecific CLL-1xCD3 BiTE Antibody
Sensitivity of Pediatric Acute Leukemia Cells to Bortezomib and Epoxyketone-Based Proteasome Inhibitors: Correlations with Proteasome Subunit Expression
How I treat: kleine klonen, grote gevolgen
How I treat “schimmel”
“How I treat”: Trombotische trombocytopenische purpura
Uniparental isodisomy and progressive clonal selection: a common mechanism causing late onset beta-thalassemia Major?
Increasing the dose of rabbit-ATG does not lead to a higher response rate in the first line treatment of severe aplastic anemia
Arterial thrombosis in Von Willebrand Disease
Hemarthrosis results in an increase in Articular Fibrinolytic activity in Hemophilic Mice
Response to desmopressin in hemophilia A patients with low FVIII levels
Voriconazole concentrations are significantly influenced by inflammatory reactions
Past, present, and future of Myelodysplastic syndromes

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