Home » Journal nummers » Jaargang 12, Abstractboek, Februari 2015

Inhoudsopgave Jaargang 12, Abstractboek, Februari 2015

Abstractbooks

Increased incidence of T-cell malignancies in patients with chronic lymphocytic leukaemia
Outcome and minimal residual disease monitoring in adult acute lymphoblastic leukemia patients treated with pre-induction therapy (Groningen regimen)
Improving hospital care for patients with non-Hodgkin’s lymphomas: preliminary results of a clustered randomized controlled trial
Bone-marrow niche derived R-spondins facilitate Wnt/β-catenin signalling in multiple myeloma via aberrantly expressed LGR4
Understanding the role of B-cell receptor signaling in development of chronic lymphocytic leukemia using novel mouse cell lines
Long noncoding RNAs, a novel component of the Myc transcriptional network
NF-kB signaling prevents DNA damage in pre-B cells by suppressing RAG1/2 expression and activity
Oncogenic miRNAs in Hodgkin lymphoma cell lines
Prevalence of hematological abnormalities in potential stem cell donors
The comparative value of hematopoietic stem cell transplantation and chemotherapy in cytogenetically normal AML subclassified by NPM1 mutation status and FLT3-ITD allelic ratio
Post-remission treatment with allogeneic stem cell transplantation improves outcome in patients aged 60 years and older with acute myeloid leukemia in first remission
A rationale for reduced-frequency dosing of anidulafungin for antifungal prophylaxis in immunocompromised patients
Superiority of (in vitro) 3D niche-mimicking system applied in MSC and HSC co-culturing and its impact on hematopoietic support
The humanized scaffold model 2.0: Implementation of human blood vessels in human bone-marrow-like scaffold model
Establishing human niche xenograft models for myeloid and lymphoid leukemia driven by MLL-AF9
CLL development is accelerated in mice deficient for pro-apoptotic regulator Noxa
Age dependent HLA associations in classical Hodgkin lymphoma
Screening for affinity divergent CD38 antibodies and their translation into CD38 Chimeric antigen receptors
Determining and manipulating MCL-1 expression in primary B cell malignancies
Integrated V617F, exon 12, and mutational screening in myeloproliferative neoplasms by next generation sequencing
Erythroid analysis by flow cytometry strongly adds to MDS diagnosis: A report on behalf of the HOVON89 Study Group
Identification of chromosomal abnormalities by microarray-based genomic profiling as compared to karyotyping in patients with low and intermediate-1 risk myelodysplastic syndromes within a prospective clinical trial: a study on behalf of the HOVON89 Study Group
Towards a further refinement of current risk classification in acute myeloid leukemia
Extensive Molecular Analysis Strongly Improves the Distinction Between AML and ALL in Adult acute leukemias of ambiguous lineage
Trends in incidence, primary treatment and survival of chronic myelomonocytic leukemia: a nationwide population-based study among 1,359 patients diagnosed in the Netherlands from 1989 to 2012
Streptamer isolated multi-antigen specific T cells contain tumor associated antigen reactive donor T cells as elementary component
The aryl hydrocarbon receptor antagonist stemregenin 1 stimulates expression of NK cell related transcription factors, thereby it facilitates generation of highly functional NK cells in vitro
The mutational landscape of Hodgkin lymphoma cell lines determined by whole-exome sequencing
TCRgd+ T-LGL cells are effector TCRgd+ T cells with disturbed proliferation and apoptosis
Co-operative role of colony stimulating factor 3 receptor and runt-related transcription factor 1 mutations in leukemic progression from severe congenital neutropenia
Mutations in ELANE and HAX1 lead to elevated ROS levels and diminished hematopoietic differentiation potential in an human induced pluripotent stem cell model of severe congenital neutropenia
Selective mRNA translation controls erythropoiesis: regulation and function of the RNA-binding protein Csde1
Increased formation and increased degradation of fibrin clots in solvent-detergent plasma: a 72 hour observation study between Omniplasma and Quarantine plasma
Influence of INR level on the agreement between capillary and venous INR results
Population pharmacokinetics in Hemophilia A: Towards individualization of perioperative replacement therapy
Overdosing of replacement therapy in perioperative von Willebrand patients: a need for patient-tailored therapy
Combining lenalidomide and cyclophosphamide is synergistic and has clear immune-modulating effects in lenalidomide refractory patients
Modulation of CD38 expression levels on multiple myeloma cells by all-trans retinoic acid improves the efficacy of the anti-CD38 monoclonal antibody daratumumab
Anaemia in general practice: causes and survival
Characterisation of reticulocyte differentiation: from in vivo to in vitro
Complement activation in AIHA as footprint for difficult-to-detect IgM-autoantibodies
Increased risk of development of malignancies in adult patients treated with antithymocyte globulin as first line treatment for acquired aplastic anaemia
An alternative ITGB2 splice variant encodes a novel hematopoietic restricted minor histocompatibility antigen with therapeutic relevance
Inhibition of Akt-signalling promotes the generation of superior tumour-reactive T cells for adoptive immunotherapy
In vitro generation of HLA-DP-restricted donor T cells with hematopoiesis specificity
T-cell receptors (TCRs) specific for the intracellular transcription factor Bob1 allow efficient targeting of human B-cell leukemia and multiple myeloma

Abstracts van het 9e Dutch Hematology congress 2015

Ex vivo generation of human plasmacytoid and myeloid dendritic cell-based vaccines from CD34+ hematopoietic progenitor cells
Vitiligo after allogeneic stem cell transplantation associated with the presence of donor CD4 T-cells recognizing a melanocyte specific MiHA
High DNA-methyltransferase 3B expression predicts poor outcome in acute myeloid leukemia, especially among patients with co-occurring NPM1 and FLT3 mutations
Phosphoproteomics of a panel of AML cell lines reveals oncogenic signaling and candidate drivers
Clonal analysis of human hematopoiesis by cellular barcoding
Potent human graft versus acute leukemia responses are mediated by cytotoxic antibodies
Massive parallel sequencing of full-length B-cell receptor sequences reveals HLA-dependent shaping of the B-cell immune repertoire
Dendritic cell subsets in myelodysplastic syndromes
Essential role for non-canonical PRC1.1 in leukemia independent of the canonical PRC2/PRC1 axis
Loss of ASXL1 triggers an apoptotic response in human hematopoietic stem and progenitor cells
Tumor suppressor genes and cooperate in leukemia development and glucocorticoid therapy resistance
miRNA-125a expands multilineage long-term repopulating activity to hematopoietic stem cells and multipotent progenitors

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