Inleiding In 1982 is het antilichaam (Ki-1) ontdekt dat specifiek het antigeen CD30 herkent op reed-sternberg-cellen in hodgkinlymfoom.1,2 Dit an… Lees verder »
Introduction Relapse of acute myeloid leukemia (AML) is thought to be the result of outgrowth of therapy resistant leukemic stem cells (LSC). Pre… Lees verder »
Inleiding In de geschiedenis van de hemato-oncologie bleek het hodgkinlymfoom (HL) de eerste maligniteit welke te genezen bleek met chemo- en/of… Lees verder »
Introduction Despite significant improvements in the treatment of multiple myeloma (MM), this progressive malignancy of antibody-producing clonal… Lees verder »
Introduction C-Met is a proto-oncogene that encodes for the Hepatocyte Growth Factor (HGF) receptor. Upon stimulation with HGF, c-Met gives rise… Lees verder »
Introduction Background: Little is known about the course of fatigue and health-related quality of life (HRQOL) in non-Hodgkin lymphoma (NHL) sur… Lees verder »
Introduction Hodgkin lymphoma (HL) is characterized by constitutive activation of several signaling pathways and expression of a distinct set of… Lees verder »
Introduction The tumor cells of Hodgkin lymphoma (HL) are derived from germinal center (GC) B cells that have escaped from apoptosis. MicroRNAs (… Lees verder »
Introduction Classical Hodgkin lymphoma (cHL) is characterized by a bimodal age incidence curve. In the western world, the first prominent peak i… Lees verder »
Introduction The pathogenesis of classic Hodgkin lymphoma (cHL) involves environmental and genetic factors. Epstein Barr Virus (EBV) is a well kn… Lees verder »
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